VISDB Viral Integration Site DataBase

VIS ID

TVIS10006895

Fusion event

HBV-FN1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

B2

Reference genome

Region type

pre-core/core

Start

2032

Integrated sequence

TTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCT| |CCGGAACATTGTTCACCTCACCATACGGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTAGCCACCTGGGTGGGAAGTAATTTGGAAG

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216248976/215384253 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1626094; hsa-mir-1244-1/Downstream/2516260;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/71844, chr2-CpG: 43/Downstream/51291

Upstream sequence

ACAGTGAACTCCTGGACAGGGCTATTTCCTCCTGTATGAAAAAGGGTTAGTTCAGAGTGTGAGGGGTTTAGAGCTACTTGGGTATTACTGATTAATTGAA

Downstream sequence

TTACCACATTTATAGCAGCATGTAAATCACATCTTCTTGCTTATTCCCTTTTAAAGAGCGCTATCTTGAACAGAAAGGGGTATTTATGCATGTAGCAAAC