Basic Information
VIS ID
TVIS10006898
Fusion event
HBV-chr12 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
JQ688405
Region type
pre-core/core, X protein
Start
1818
Integrated sequence
GTGTTTAATGAGTGGGAGGAGTTGGGGGAGGAGGTTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTGTGTTCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTAT
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
95339/10399 (Hg38)
End
95339/10399 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Downstream/1649916;
Nearest TSS
ENST00000382841/Downstream/27703;
Nearest CpG islands
None/Target, None/Upstream, chr12-CpG: 104/Downstream/20390
Nearby gene
FAM138D(No orient, 52607)
Upstream sequence
ggttggggttggggttagggttagggttagggttagggtagggttagggttagggttaggggttaggggttaggggttagggttagggttagggttaggg
Downstream sequence
tagggttagggttagggttagggttagggtagggttagggttagggttaggggttagggttagggttagggttagggttacggtttggggttggggttag
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate