VISDB Viral Integration Site DataBase

VIS ID

TVIS10006899

Fusion event

HBV-SHISA6 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

B2

Reference genome

Region type

Polymerase,S

Start

409

Integrated sequence

TTCGCAGTCCCAAATCTCCAGTCACTCACCAACCTGTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTGC| |ATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCATCAACAACCAGCACCG

Chromosome

chr17

Cytoband

p12

Reference genome

Start

End

11427797/11524480 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-5196-5p ; hsa-mir-6797-5p ; hsa-mir-4747-5p ; hsa-mir-1249-5p ; hsa-mir-4683 ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-873-5p ; hsa-mir-4708-5p ; hsa-mir-9500 ; hsa-mir-4459 ; hsa-mir-4779 ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-491-5p ; hsa-mir-7847-3p ; hsa-mir-92a-2-5p ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-7106-5p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-766-5p ; hsa-mir-3665 ; hsa-mir-6134 ; hsa-mir-3928-3p ; hsa-mir-6777-5p ; hsa-mir-6889-5p ; hsa-mir-194-3p ; hsa-mir-5693 ; hsa-mir-2278 ; hsa-mir-6875-3p ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-4778-3p ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-6731-3p ; hsa-mir-499b-5p ; hsa-mir-4494 ; hsa-mir-506-5p ; hsa-mir-892c-5p ; hsa-mir-3680-5p ; hsa-mir-6741-3p ; hsa-mir-6867-3p ; hsa-mir-6749-3p ; hsa-mir-6826-3p ; hsa-mir-1298-5p ; hsa-mir-7110-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-205-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-5193 ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-502-5p ; hsa-mir-1915-5p ; hsa-mir-6841-3p

Nearest miRNA

hsa-mir-1253/Upstream/3337476; hsa-mir-10226/Downstream/557419;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/282381, chr17-CpG: 32/Downstream/33274

Upstream sequence

CTCATAGATAAAAAATTAGCAGCATGTTTTTAAAAACCAAGGTATTTATCTAGGTAGTGGGCTTATAGATAATTTTATTTATTTTTCCATAAtttctttt

Downstream sequence

ctttttttcttttttcttttttctttttttttttgagatggagttttgctcttttgcccaggctagagtgaaatggtgtgatctcagctcaccacaacct