PCK2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006905
Fusion event
HBV-PCK2 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
JQ688405
Region type
X protein
Start
1757
Integrated sequence
GAGGACTCTTGGACTTTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTGTTTAATGAGTGGGAGGAGTTGGGGGAGGAGGTTAGG| |TTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTGTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCC
Host Sequence
Chromosome
chr14
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
24560713/24091504 (Hg38)
End
24560713/24091504 (Hg38)
Location type
Promoter
Target gene
PCK2
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-208a/Upstream/673441; hsa-mir-1185-1/Downstream/51985;
Nearest TSS
ENST00000550708/Upstream/6879; ENST00000560657/Downstream/2549;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/9565, chr14-CpG: 57/Downstream/2543
Upstream sequence
CACAGAAGTGCTCTGGAAACTTCAGAGTTCAGTACGTAGGAGAAAAGGAGGCAAGTGGGGATGTGGGGGTGACAACATTAGATAAATAGGAGTCAGATTA
Downstream sequence
TGAAGGACATAAGATATCATGTGATGGAAAGAGCCTGGAAGAGATTTTAAGCTTAAGAGTGATATGATCTAATTTTTAATGGTAAATCAAGgggacagta
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate