Basic Information
VIS ID
TVIS10006911
Fusion event
HBV-chr5 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
Polymerase;X protein
Start
1403
Integrated sequence
GCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGGTGTGCTGCCAACTGGAT| |CCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCATCTG
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
10480/10480 (Hg38)
End
10480/10480 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Downstream/1052416;
Nearest TSS
ENST00000502646/Downstream/81671;
Nearest CpG islands
None/Target, None/Upstream, chr5-CpG: 87/Downstream/40210
Upstream sequence
CAGGTCCGGACGCGGGGCGTCGGGCTCCGGGCACCACGAATGCCGGACGTGAAGGGGAGGACGGAGGCGCGTAGACGCGGCTGGGGACGAACCCGAGGAC
Downstream sequence
taaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaac
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
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