VISDB Viral Integration Site DataBase

VIS ID

TVIS10006913

Fusion event

HBV-SASH1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

C2

Reference genome

Region type

Polymerase,S

Start

460

Integrated sequence

TCCTGGCTATCGCTGGATGTGTCTGCGGCGTTTTATCATATTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGT| |ATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCT

Chromosome

chr6

Cytoband

p12.3

Reference genome

Start

End

48795259/48827622 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-93-5p ; hsa-mir-181a-5p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-3944-5p ; hsa-mir-548q ; hsa-mir-8083 ; hsa-mir-4700-3p ; hsa-mir-4744 ; hsa-mir-4773 ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-7156-3p ; hsa-mir-1262 ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-4325 ; hsa-mir-4504 ; hsa-mir-4701-3p ; hsa-mir-508-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-92a-3p ; hsa-mir-92b-3p

Nearest miRNA

hsa-mir-10398/Upstream/3629852; hsa-mir-10524/Downstream/3316727;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/758728, chr6-CpG: 20/Downstream/635599

Nearest cancer related gene

SASH1(TSG, No orient, 0)

Upstream sequence

GTCATCCCTCCCTTCTGGTAAGAAAGGATTGCCAggccgggcgcggtggctcaagcctgtaatcccagcactttgggaggctgaggtgggtggctcacga

Downstream sequence

CAGGCCAGGTTTTTCCTGGAACAGTGGGGTGGGGCTTTGGGGGGCGGTTTGAacgagaagagtcaaactttgtaaaatacttgaagagatttattctgag