Fusion event
HBV-STX8 integration
Detection method
Alu PCR and sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
Polymerase,Pre-S2/S, S
Integrated sequence
CTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTC| |AATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAACACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTG
End
9239789/9336472 (Hg38)
Nearest miRNA
hsa-mir-1253/Upstream/1149468; hsa-mir-10226/Downstream/2745427;
Upstream sequence
tttccttcctttctttctccccttccccttcctcccttccttccccttccttccttccccttccttccttctttctttcttgagatggagtctcactctg
Downstream sequence
tgtcccaggctggagtgcagtggcacgatctcagctcactgcaacctccgcttcccaggttaaagcaattctcctgcctcagcctcccgagttgctggga
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.