VISDB Viral Integration Site DataBase

VIS ID

TVIS10006917

Fusion event

HBV-GAS7 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

C2

Reference genome

Region type

Polymerase,S

Start

556

Integrated sequence

AGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTT| |CCCTCTTGTTGCTGTACAAAACCTTCGGACGGAAACTGCACTTGTATTCCCATCCCATCATCCTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAG

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

9899107/9995790 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-128-3p ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-1255b-5p ; hsa-mir-6744-5p ; hsa-mir-1255a ; hsa-mir-1287-5p ; hsa-mir-4487 ; hsa-mir-450b-5p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-3124-3p ; hsa-mir-6837-3p

Nearest miRNA

hsa-mir-1253/Upstream/1808786; hsa-mir-10226/Downstream/2086109;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/90768, chr17-CpG: 142/Downstream/201927

Upstream sequence

atgcctgtctgtgaaaggtaatttggagatatccatcaaaagcccaaatgcacgtgtcttttgacctaacaatagctttaggtgtgcaataatgtaagta

Downstream sequence

tgaaggtattttgtggagcacttttcattagagggaaaagactcttgggaagtgacctaaatgttcaccaacaggggacAATGATGTATCGACAGGGTGG