VISDB Viral Integration Site DataBase

VIS ID

TVIS10006918

Fusion event

HBV-MTA3 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

C2

Reference genome

Region type

Polymerase

Start

1369

Integrated sequence

ACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCT| |TTCCATGGCTGCTAGGGTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGG

Chromosome

chr2

Cytoband

p21

Reference genome

Start

End

42751374/42524234 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-296-3p ; hsa-mir-495-3p ; hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-6832-3p ; hsa-mir-153-5p ; hsa-mir-4687-5p ; hsa-mir-4422 ; hsa-mir-330-3p ; hsa-mir-4278 ; hsa-mir-6789-5p ; hsa-mir-6824-5p ; hsa-mir-4294 ; hsa-mir-6758-3p ; hsa-mir-4528 ; hsa-mir-6782-5p ; hsa-mir-6873-3p ; hsa-mir-7110-3p ; hsa-mir-6817-3p ; hsa-mir-4639-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-6845-3p ; hsa-mir-337-3p ; hsa-mir-4789-5p ; hsa-mir-1284 ; hsa-mir-570-3p ; hsa-mir-5001-3p ; hsa-mir-6722-5p ; hsa-mir-4772-3p ; hsa-mir-6787-3p ; hsa-mir-1304-3p ; hsa-mir-6736-3p ; hsa-mir-6890-3p ; hsa-mir-652-3p ; hsa-mir-216a-5p ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-875-3p ; hsa-mir-4446-5p ; hsa-mir-4755-5p ; hsa-mir-5006-3p ; hsa-mir-642a-5p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-1224-3p ; hsa-mir-141-5p ; hsa-mir-3152-5p ; hsa-mir-6809-3p ; hsa-mir-6836-3p ; hsa-mir-4753-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-8062 ; hsa-mir-1273f ; hsa-mir-129-5p ; hsa-mir-143-3p ; hsa-mir-4670-3p ; hsa-mir-4708-5p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-8055

Nearest miRNA

hsa-mir-1301/Upstream/7052748; hsa-mir-10b/Downstream/4853441;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/29208, chr2-CpG: 32/Downstream/44515

Upstream sequence

CCATGGTTCTAGATTGGAAACTCCTCAAGCCATTGGAGACACAAAGTAGTTCCTGGGCTTTGTACACTCTTCCCCTGGTAAAATTCCTGTCTTTCCCACA

Downstream sequence

CCACTCCCTTTGATTGACCTCCTGAAAAAGAGCATATGTTCAGCTTCAATGGTTGCAACCATTATTATTAtttttttttttttttaaatggagtctcacc