Basic Information
VIS ID
TVIS10006919
Fusion event
HBV-chr5 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
Polymerase, X protein
Start
1546
Integrated sequence
CCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCT| |CCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAG
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
11784/11784 (Hg38)
End
11784/11784 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Downstream/1051112;
Nearest TSS
ENST00000502646/Downstream/80367;
Nearest CpG islands
None/Target, None/Upstream, chr5-CpG: 87/Downstream/38906
Nearby gene
PLEKHG4B(No orient, 128589)
Upstream sequence
ATCCACTGGGAGCCCGGCCTGGCCCCGACAGCGCAGCTGCTCCGGGCGGACCCGGGGGTCTGGGCCGCGCTTCCCCGCCCGCGCGCCGCTCGCGCTCCCA
Downstream sequence
taacccctaaccctaaccctaaaccctaaccctgaacccgaaccctgacccctgacccctgaccccgaccccgaccccgaccccgaccctgaccctaTGC
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
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