VISDB Viral Integration Site DataBase

VIS ID

TVIS10006924

Fusion event

HBV-PCMTD2 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

B2

Reference genome

Region type

Polymerase, S

Start

666

Integrated sequence

GCTGTACAAAACCTACGGACGGAAACTGCACCTGTATTCCCATCCCATCATCTTGGGCTTTCGCAAAATACCTATGGGAGTGGGCCTCAGTCCGTTTCTC| |TTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTCTGGCTTTCAGTTATATGGATGATGTGGTTTTGGGGGCCAAGT

Chromosome

chr20

Cytoband

q13.33

Reference genome

Start

End

62918375/64287022 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-142-3p ; hsa-mir-23b-3p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-365a-3p ; hsa-mir-365b-3p ; hsa-mir-4457 ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-6506-3p ; hsa-mir-935 ; hsa-mir-5094 ; hsa-mir-6505-5p ; hsa-mir-9-5p ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-1-1/Upstream/210012;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/16461, chr20-CpG: 92/Downstream/29273

Upstream sequence

gtcaggggttagggtcggggtcggggtcggggtcaggggtcaggggtcaagggtcggggtcaggggtcggggtcagggtgagggtgagggtgagggttag

Downstream sequence

gggttagggttagggttagggttacggttagggttagggttagggttagggtagggttagggttaggggttaggggttagggttagggttagggtaaggg