VISDB Viral Integration Site DataBase

VIS ID

TVIS10006927

Fusion event

HBV-PCMTD2 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

C2

Reference genome

Region type

Polymerase, X protein

Start

1486

Integrated sequence

TGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACC| |GTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTT

Chromosome

chr20

Cytoband

q13.33

Reference genome

Start

End

62918250/64286897 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-142-3p ; hsa-mir-23b-3p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-365a-3p ; hsa-mir-365b-3p ; hsa-mir-4457 ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-6506-3p ; hsa-mir-935 ; hsa-mir-5094 ; hsa-mir-6505-5p ; hsa-mir-9-5p ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-1-1/Upstream/209887;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/16336, chr20-CpG: 92/Downstream/29398

Upstream sequence

tagggttagggttagggttagggttagggtagggtcagggtcagggtcagggtcagggtcagggttaagggtcagggtcagggtcagggtcagggtcagg

Downstream sequence

ggttagggttagggttagggtcagggtcaggggttagggtcggggtcggggtcggggtcaggggtcaggggtcaagggtcggggtcaggggtcggggtca