ALB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006930
Fusion event
HBV-ALB integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
Polymerase; pre-S1/pre-S2/S
Start
2936
Integrated sequence
AGAGCTACAGCATGGGAGGTTGGTCTTCCAAACCTCGACAAGGCATGGGGACGAATCTTTCTGTTCCCAATCCTCTGGGATTCTTTCCCGATCACCAGTT| |GGACCCTGCGTTCGGAGCCAACTCAAACAATCCAGATTGGGACTTCAACCCCAACAAGGATCACTGGCCAGAGGCAAATCAGGTAGGAGCGGGAGCATTC
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
74271597/73405880 (Hg38)
End
74271597/73405880 (Hg38)
Location type
Intronic
Target gene
ALB
miRNAs that regulate target gene
hsa-mir-492
Nearest miRNA
hsa-mir-12113/Upstream/7128952; hsa-mir-1243/Downstream/3167688;
Nearest TSS
ENST00000502981/Upstream/1572; ENST00000507673/Downstream/2758;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/146467, chr4-CpG: 20/Downstream/214447
Upstream sequence
TAATACAAAATTACCTTAAATGACCTAAAAAATTTAAATTTAGTATGTATTTTGCAGGTGAAAGACGGCTGTCATACAGAGCACTTCAGGGAGCATTGAT
Downstream sequence
cccggccTATTTAAATGTTTTTTAATCTAGTAAAAAATGAGAAAATTGTTTTTTTAAAAGTCTACCTAATCCTACAGGCTAATTAAAGACGTGTGTGGGG
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate