Basic Information
VIS ID
TVIS10006932
Fusion event
HBV-chr19 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
Polymerase, X protein
Start
1408
Integrated sequence
TCTGGAGCGAAACTTATCGGAACCGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGGTGTGCTGCCAACTGGATCCTGC| |GCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCATCTGCCGTT
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
32790314/32299408 (Hg38)
End
32790314/32299408 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10395/Upstream/11900054; hsa-let-7e/Downstream/2823292;
Nearest TSS
ENST00000633603/Upstream/193492; ENST00000587084/Downstream/46186;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/74624, chr19-CpG: 52/Downstream/46039
Nearby gene
ZNF507(No orient, 46200)
Upstream sequence
gtcttattcctgatattagaggaaatgattcagcttttcactgttgagtttaatgttatctgtgggcttgtcatatatggcctttattatgttgaggtgc
Downstream sequence
attccttctacacctaatttgttgagagtttttatcatgaaattatgttgaattttgtcaaatgcttttttgctcttattgagacgatcatatggttttt
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate