Basic Information
VIS ID
TVIS10006939
Fusion event
HBV-chr10 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
JQ688405
Region type
Polymerase,S
Start
574
Integrated sequence
TCCTCTAATTCCAGGATCATCAACAACCAGCACCGGACCATGCAAAACCTGCACAACTCCTGCTCAAGGAACCTCTATGTTTCCCTCATGTTGCTGTACA| |AAACCTACGGACGGAAACTGCACCTGTATTCCCATCCCATCATCTTGGGCTTTCGCAAAATACCTATGGGAGTGGGCCTCAGTCCGTTTCTCTTGGCTCA
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
135524437/133787112 (Hg38)
End
135524437/133787112 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/415449;
Nearest TSS
ENST00000439456/Upstream/160317;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/25865, None/Downstream
Nearby gene
DUX4L8(No orient, 25945)
Upstream sequence
ttcctaatgcacacatgacaccctaaatataacaggcatattactcatggagggttagggttcaggttcgggtacgggttcaggttcgggttcgggttcg
Downstream sequence
ggttccggttcgggttaggggttagggttgggttagggttagggttagggttagggttagggttagggttagggtttagggtcagggtcagggtcagggt
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate