VISDB Viral Integration Site DataBase

VIS ID

TVIS10006941

Fusion event

HBV-STXBP4 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

B2

Reference genome

Region type

Polymerase

Start

1342

Integrated sequence

ACCTTTGTGTCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGGGCAAAACTCATCGGGACTGACAATTCTG| |TCGTGCTCTCCCGCAAGTATACATCATTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCT

Chromosome

chr17

Cytoband

p13.3

Reference genome

Start

End

3048221/3144927 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-324-5p ; hsa-mir-7702 ; hsa-mir-151a-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-4448 ; hsa-mir-3670 ; hsa-mir-556-5p

Nearest miRNA

hsa-mir-1253/Upstream/396745; hsa-mir-10226/Downstream/1824775;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/95848, chr17-CpG: 81/Downstream/241141

Upstream sequence

gttcaatttcattgatttttgatcctatcattattacttccttccttgtgtttgctttgaatttattttgctcttttctaggcttcttaaatgggaactt

Downstream sequence

agattattgatttgagactttcctcttttctaatgtatgtattcagtgctatacattttcttcttatcattgttctagctttgttccacaaattctgata