Basic Information
VIS ID
TVIS10006944
Fusion event
HBV-DUX4L8 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
Region type
Polymerase, X protein
Start
1595
Integrated sequence
TCCGCCTGTTGTACCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACC| |TCTGCACGTCGCATGGAGACCACCGTGAACGCCCACAGGAACCTGCCCAAGGTCTTGCATAAGAGGACTCTTGGACTTTCAGCAATGTCAACGACCGACC
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
End
135524639/133787314 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-107/Upstream/415651;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/26067, None/Downstream
Upstream sequence
gggtcagggtcagggttaggggttagggtcggggtcggggtcggggtcggggtcagggtcagggtcagggtgagggtgagggtgagggtgagggtcaggg
Downstream sequence
tgagggtgagggtgagggtgagggttagggtgagggttagggttagggttagggtgagggttagggttagggtgagggttagggttagggtgagggttag
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate