Basic Information
VIS ID
TVIS10006947
Fusion event
HBV-CENPBD1P1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
Polymerase, S
Start
509
Integrated sequence
ATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGG| |GACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGTACAAAACCTTCGGACGGAAACTGCACTTGTATTCCCAT
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
GRCh37/hg19
Start
59098041/58586674 (Hg38)
End
59098041/58586674 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
CENPBD1P1
Nearest miRNA
hsa-let-7e/Upstream/36298;
Nearest TSS
ENST00000633603/Upstream/13099; ENST00000596029/Downstream/12603;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/4768, None/Downstream
Upstream sequence
agggtcagggtcagggtcagggtcagggtcagggttagggtttagggtcagggtcagggtcagggtcagggttagggtagggttagggttagggttaggg
Downstream sequence
ttagggtagggttagggttagggttagggttagggtATTGTAAATAATTTCACATTACTAATAATAAATTATTATTTGTATTACACTATTACGTAATGTA
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate