Basic Information
VIS ID
TVIS10006953
Fusion event
HBV-CCND2-AS1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
Polymerase,S
Start
663
Integrated sequence
GTTGCTGTACAAAACCTTCGGACGGAAACTGCACTTGTATTCCCATCCCATCATCCTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTT| |CTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCA
Host Sequence
Chromosome
chr12
Cytoband
p13.32
Reference genome
GRCh37/hg19
Start
4368524/4259358 (Hg38)
End
4368524/4259358 (Hg38)
Location type
Intronic
Target gene
CCND2-AS1
Nearest miRNA
hsa-mir-3649/Upstream/2598978; hsa-let-7i/Downstream/2704341;
Nearest TSS
ENST00000382841/Upstream/233373; ENST00000541542/Downstream/14414;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/15295, chr12-CpG: 379/Downstream/9878
Upstream sequence
tttttctctcctccttctgacactccaattatgtgtatgttggtaggcttgatggtgccccacaggtctctaagactctgttcatttttcttcattattc
Downstream sequence
ttttttctctgtttctcagactggatgatctcaattaacacagcttcaagttaggtgattctttcttctgctagttcaaatctgctattgagcccctgcc
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate