Basic Information
VIS ID
TVIS10006959
Fusion event
HBV-chr5 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
JQ688405
Region type
Polymerase,S
Start
712
Integrated sequence
ATCATCTTGGGCTTTCGCAAAATACCTATGGGAGTGGGCCTCAGTCCGTTTCTCTTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTT| |TCCCCCACTGTCTGGCTTTCAGTTATATGGATGATGTGGTTTTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTATGCCGCTGTTACCAATTTTCT
Host Sequence
Chromosome
chr5
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
51223925/51928091 (Hg38)
End
51223925/51928091 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA5H
Nearest miRNA
hsa-mir-10397/Upstream/13370530; hsa-mir-103a-1/Downstream/2023413;
Nearest TSS
ENST00000502646/Upstream/476933; ENST00000505899/Downstream/79940;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/528573, chr5-CpG: 34/Downstream/860021
Nearby gene
KATNBL1P4(+2602) ;
Upstream sequence
atacaaaggaaacagggtgcctttacactgagctagccggcagacacccccttaaccaagtgatcaaactaaggatcccaaacagtgagacaaggcggca
Downstream sequence
gcaattgtatacccactggaacacttaaggtaaagctaaccagggaagatggcatcctttatgtgaacagcttttcacaagatcacagatcaggacttct
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate