Basic Information
VIS ID
TVIS10006964
Fusion event
HBV-chr16 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
Polymerase,S
Start
516
Integrated sequence
TGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATG| |CAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGTACAAAACCTTCGGACGGAAACTGCACTTGTATTCCCATCCCATCA
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
69784/19784 (Hg38)
End
69784/19784 (Hg38)
Nearest miRNA
hsa-mir-6859-4/Upstream/2665; hsa-mir-11401/Downstream/515532;
Nearest TSS
ENST00000527434/Downstream/3126;
Nearest CpG islands
None/Target, None/Upstream, chr16-CpG: 29/Downstream/3059
Nearby gene
DDX11L10(-1693) ; WASIR2(+3132) ;
Upstream sequence
ccactgaaccctaacaccgaccctgaaccctaaccccgaccctcaccctgaccctcaccctaccctgaccctcaccctgaccctgaccctgaccctcacc
Downstream sequence
ctgaccctgactctgaccctgaccctgaccctgactctaaccctaaccctgaccctgaccctgaccctgaccctgacccttgaccctgaccctgaccctg
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
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