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VISDB
Viral Integration Site DataBase
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TVIS10006968
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006968
Fusion event
HBV-KMT2B integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
Polymerase,S
Start
504
Integrated sequence
TCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAG| |CACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGTACAAAACCTTCGGACGGAAACTGCACTTGTATT
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
6212721/6212710 (Hg38)
End
6212721/6212710 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
KMT2B
miRNAs that regulate target gene
hsa-mir-7515
;
hsa-mir-302a-5p
;
hsa-mir-3154
;
hsa-mir-6782-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-5692a
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-93-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-20b-5p
;
hsa-mir-153-3p
;
hsa-mir-1224-3p
;
hsa-mir-1294
;
hsa-mir-1914-3p
;
hsa-mir-214-3p
;
hsa-mir-31-5p
;
hsa-mir-3184-5p
;
hsa-mir-3619-5p
;
hsa-mir-3689d
;
hsa-mir-423-5p
;
hsa-mir-4316
;
hsa-mir-4426
;
hsa-mir-4440
;
hsa-mir-4459
;
hsa-mir-4647
;
hsa-mir-4662b
;
hsa-mir-4688
;
hsa-mir-4722-5p
;
hsa-mir-5194
;
hsa-mir-6085
;
hsa-mir-6165
;
hsa-mir-6734-5p
;
hsa-mir-6738-5p
;
hsa-mir-6743-5p
;
hsa-mir-6789-5p
;
hsa-mir-6813-5p
;
hsa-mir-6851-5p
;
hsa-mir-761
;
hsa-mir-7704
;
hsa-mir-885-3p
Nearest miRNA
hsa-mir-1227/Upstream/1279970; hsa-let-7e/Downstream/176928;
Nearest TSS
ENST00000633603/Upstream/1234;
ENST00000588192/Downstream/4258;
Nearest CpG islands
chr19-CpG: 90/Target
, None/Upstream, None/Downstream
Upstream sequence
GCGGAGGGTGTGTTCTGAACCATTCGGGAGGCTGGAGATGCCCCCCAGCCGTCGATCCGCTGCTCAGAAAGGCTGGGGCAGCGACGCCGCACAGCCCGCC
Downstream sequence
GAGCAGTGGGGGCTGGTCCCAAGGCTGGGCGAGGGGCCCCCGGCCCTGTCTCTGCCCAGAGCTGCCTTCAACACCAGCCGCTCTCTGAGGGGAGCCCAGA
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Sample Information
×
Sample name
G-21T
Sample type
Tumor
Gender
Female
CpG Island Information
×
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