Basic Information
VIS ID
TVIS10006971
Fusion event
HBV-chr22 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
JQ688405
Region type
Polymerase,Pre-S2/S,S
Start
137
Integrated sequence
GTCAGGGCCCTGTACTTTCCTGCTGGTGGCTCCAGTTCAGGAACAGTGAGCCCTGCTCAGAATACTGTCTCTGCCATATCGTCAATCTTATCGAAGACTG| |GGGACCCTGTACCGAACATGGAGAACATCGCATCAGGACTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAAAATCCTCACAAT
Host Sequence
Chromosome
chr22
Cytoband
p12
Reference genome
GRCh37/hg19
Start
5465915/5465915 (Hg38)
End
5465915/5465915 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7a-3/Downstream/12298265;
Nearest TSS
ENST00000624155/Downstream/5600503;
Nearest CpG islands
None/Target, None/Upstream, chr22-CpG: 279/Downstream/5059571
Nearby gene
PHF21B(No orient, 60106)
Upstream sequence
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Downstream sequence
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
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