NRG1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006996
Fusion event
HBV-NRG1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1828
End
2213
Orient
+
Host Sequence
Chromosome
chr8
Cytoband
p12
Reference genome
GRCh37/hg19
Start
31613530/31756014 (Hg38)
End
31613530/31756014 (Hg38)
Orient
+
Location type
Intron
Target gene
NRG1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-125a-3p
Nearest miRNA
hsa-mir-124-1/Upstream/1798666; hsa-mir-10400/Downstream/9515034;
Nearest TSS
ENST00000518652/Upstream/115588; ENST00000523320/Downstream/415368;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/115184, chr8-CpG: 169/Downstream/791875
Upstream sequence
GATAGATCAGACAATAAATGCACAAGTTGTATCCTATTAAATTGTTAAAAACTGTAACAACAATAACAACAAAAATCACTGGCTTAATAACTAGATTAGC
Downstream sequence
CATACCCCTCTGTTTGATTAGCTAGACATCTAAATCCATGCAAAGCATTGTTTATATAACACAATCTGCAAGATCCTTACAGTCATAGCATCTTCATCCT
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate