Basic Information
VIS ID
TVIS10006997
Fusion event
HBV-chrX integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1820
End
2171
Orient
+
Host Sequence
Chromosome
chrX
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
97378582/98123584 (Hg38)
End
97378582/98123584 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/3060358; hsa-mir-105-1/Downstream/8516230;
Nearest TSS
ENST00000429181/Upstream/480995; ENST00000627700/Downstream/450275;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1438217, chrX-CpG: 23/Downstream/1815752
Upstream sequence
tggtagtttcttttgctgtgcagaagctctttagtttaattagatcccatttgtcaattttgtcttttgttgccattgcttttggtgttttggacatgaa
Downstream sequence
atggcaattacttttgccccaacctaataacaaccttacagaaataaaaaggataatacaaaattatgaaaaattgtgccaaaaattagataacgtagaa
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate