Basic Information
VIS ID
TVIS10007003
Fusion event
HBV-chr4 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2615
End
2882
Orient
+
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
74371982/73506265 (Hg38)
End
74371982/73506265 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/7229337; hsa-mir-1243/Downstream/3067303;
Nearest TSS
ENST00000502981/Upstream/11150; ENST00000502291/Downstream/2538;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/246852, chr4-CpG: 20/Downstream/114062
Nearby gene
AFM(-2264) ; LINC02499(+2538) ;
Upstream sequence
ATGATTTCTGATACAGATACATTTCCTAGAAAATGAGAGGGTTAAAGTTAAAGTGTATCATTAAGGCAGAATCCACTTAACTCTTAGAATTCAATGGAAA
Downstream sequence
ATTTCTATGACCTGGGCAAGAATTAAGTTTTCTATGAAAATAGTATTTATTAAACATCATCACTGCATCTTGTACTTGCATACCTTCCATATTTTATCTT
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate