Basic Information
VIS ID
TVIS10007008
Fusion event
HBV-chr12 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1579
End
1784
Orient
-
Host Sequence
Chromosome
chr12
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
77694305/77300525 (Hg38)
End
77694305/77300525 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Upstream/7715702; hsa-mir-1178/Downstream/2118732;
Nearest TSS
ENST00000382841/Upstream/71832; ENST00000552736/Downstream/24116;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/234363, chr12-CpG: 38/Downstream/1503759
Nearby gene
LOC105369855(+9432) ;
Upstream sequence
TAAGTGAGTCATTTGGTGTCAGCTGGTGATTCATAACTTACTGGATATTCTGGTTAAAATGTCAACATCGCTTAGAATGAAAATGCAGAGGTATCAAAAA
Downstream sequence
ATCAAATGTAATATTTTAGGGGAAATCAGCAGACCATTACTCTGTGACCAAGCTCTGTTAAGTGAGCATTATCTCATGGTGTTTTTGCAGAATCAGTCTT
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate