Basic Information
VIS ID
TVIS10007013
Fusion event
HBV-chr3 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1436
End
1759
Orient
-
Host Sequence
Chromosome
chr3
Cytoband
q26.31
Reference genome
GRCh37/hg19
Start
175538091/175820303 (Hg38)
End
175538091/175820303 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/450682; hsa-mir-1224/Downstream/694800;
Nearest TSS
ENST00000440867/Upstream/43970; ENST00000617758/Downstream/120734;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1378745, chr3-CpG: 133/Downstream/1376146
Nearby gene
NAALADL2(-9755) ;
Upstream sequence
ggttcaggttagggttctggttgggtttagtgttagggtttagggttagggttagggttagggttgggttagggttagggttcgggttagggttagggtt
Downstream sequence
ttaaggaatgtgtggcttctttgctcttctatccctaccaataaaagtttctctatatcagcaataaggctgttttgcttctttattatttatctgttca
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate