Basic Information
VIS ID
TVIS10007015
Fusion event
HBV-chr13 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1996
End
2133
Orient
+
Host Sequence
Chromosome
chr13
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
105978745/105326394 (Hg38)
End
105978745/105326394 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/3280390; hsa-mir-1267/Downstream/2204777;
Nearest TSS
ENST00000623511/Upstream/1901194; ENST00000640578/Downstream/139473;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2479981, chr13-CpG: 29/Downstream/1166666
Upstream sequence
CAAAACCAAACAAACTCTAAGAATTTTGAAAGTGTAGTAAAGTGAGAGATTGGGCTTTAAAAATCAAATTAATTGCTACCTTAATGAGATAATAGGAAAG
Downstream sequence
AGTTTAGCAAGCAAGCAGAAATGCTCTAAGGTTGCATTCATCCAATAATGTTTTCGTATTATGGTAGCAGTAACTTTAAATACATTTCAAGACTGTTAAA
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
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