Basic Information
VIS ID
TVIS10007018
Fusion event
HBV-chr20 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2658
End
2912
Orient
-
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
59652277/61077221 (Hg38)
End
59652277/61077221 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/512596; hsa-mir-1-1/Downstream/876325;
Nearest TSS
ENST00000382410/Upstream/263010; ENST00000441660/Downstream/595;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/52972, chr20-CpG: 261/Downstream/174700
Nearby gene
LINC01718(+1843) ;
Upstream sequence
ttcttggtattagcacacatatctttctggggatcaccatATACTTATAAATAATAAAATTGTGGACATTGTATAAACACTGATGGCATGCCAGTCAAGG
Downstream sequence
TGTTACATACTTCACTTTTGTTTGCTTATTTGATCTGATAGTCCCTATGCCATATCTCCCCCCGCTCCCAACAGGGAGTTGCACTGGACTTCCAACAagg
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate