Basic Information
VIS ID
TVIS10007025
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
487
End
784
Orient
+
Host Sequence
Chromosome
chr1
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
121484075/121742277 (Hg38)
End
121484075/121742277 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/4647549; hsa-mir-1182/Downstream/24108310;
Nearest TSS
ENST00000473358/Upstream/161753; ENST00000443018/Downstream/21758235;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/222550, chr1-CpG: 312/Downstream/3343232
Upstream sequence
ctatgaaaagcaatgttatcctctgggagttgaacacaagcctcacaaaggagtttttgagaatgcttctgtttactttttatgctagacagaagaattc
Downstream sequence
tcagtaacttccttgtgttgtgtgtattcaactcacagagttgaacgatcctttacacagagcagacttgaaacactctttttctggaatttgcaagtgg
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate