Basic Information
VIS ID
TVIS10007026
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2174
End
2409
Orient
+
Host Sequence
Chromosome
chr1
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
104518984/103976362 (Hg38)
End
104518984/103976362 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/3695054; hsa-mir-11399/Downstream/3920861;
Nearest TSS
ENST00000473358/Upstream/225956; ENST00000635102/Downstream/1629641;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/450071, chr1-CpG: 37/Downstream/2104409
Upstream sequence
GTCTTTGTCAATATACCATAAATTTTTCAGTGAATGAGTATGTTTTCTTATGACATTTATTTGAGTTATATTTTTAAAAAATCTTGAAATATATGTGGAT
Downstream sequence
GAAGCAGAGGAGAATAAAATGCAATGTTTTGGAAAACATCAGCTAGTAAATTGCTTTGTATATTTATATTGGTGAGTAACCTACAATCTGATAAAAATTA
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate