Basic Information
VIS ID
TVIS10007029
Fusion event
HBV-chr6 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1582
End
1762
Orient
+
Host Sequence
Chromosome
chr6
Cytoband
q16.3
Reference genome
GRCh37/hg19
Start
104377406/103929531 (Hg38)
End
104377406/103929531 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/4804835; hsa-mir-1202/Downstream/2854594;
Nearest TSS
ENST00000381078/Upstream/2001388; ENST00000635857/Downstream/802839;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/2526433, chr6-CpG: 79/Downstream/929713
Upstream sequence
atggtagtttcttttgctgtgcagaagctcttgagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatga
Downstream sequence
ACTATAGTAGTCAAAGCAGATTTTCtgtaaagaatttggaaaaaggtcatcacttccatttctacaggaacaaactgaaaatcaagtaactattttcgac
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate