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VISDB
Viral Integration Site DataBase
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TVIS10007031
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007031
Fusion event
HBV-TERT integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2457
End
2761
Orient
+
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
1295198/1295083 (Hg38)
End
1295198/1295083 (Hg38)
Orient
+
Location type
Promoter
Target gene
TERT
miRNAs that regulate target gene
hsa-mir-138-5p
;
hsa-mir-498
;
hsa-mir-193b-3p
;
hsa-mir-335-5p
;
hsa-mir-512-5p
;
hsa-mir-1207-5p
;
hsa-mir-1266-5p
;
hsa-mir-1182
;
hsa-mir-181a-5p
;
hsa-mir-6776-3p
;
hsa-mir-197-3p
;
hsa-mir-6740-3p
;
hsa-mir-6760-3p
;
hsa-mir-532-5p
;
hsa-mir-3064-5p
;
hsa-mir-422a
;
hsa-mir-346
;
hsa-mir-1226-3p
;
hsa-mir-1255a
;
hsa-mir-1255b-5p
;
hsa-mir-143-3p
;
hsa-mir-3161
;
hsa-mir-3605-5p
;
hsa-mir-3620-3p
;
hsa-mir-3682-3p
;
hsa-mir-4323
;
hsa-mir-4712-3p
;
hsa-mir-4733-3p
;
hsa-mir-4758-3p
;
hsa-mir-4770
;
hsa-mir-6088
;
hsa-mir-7112-3p
Nearest miRNA
hsa-mir-4635/Upstream/232109; hsa-mir-10397/Downstream/14227;
Nearest TSS
ENST00000502646/Upstream/14;
ENST00000605200/Downstream/26746;
Nearest CpG islands
chr5-CpG: 485/Target
, None/Upstream, None/Downstream
Nearest cancer related gene
TERT
(OG, No orient, 0)
Upstream sequence
CTATGCTCTATTGcaggggtgtccaatcttttagcttccctgggccacacataaaatacgctaacattacaatagctgataagctttaaaaaatggcaaa
Downstream sequence
aggaaggggaggggctgggagggcccggagggggctgggccggggacccgggaggggtcgggacggggcggggtccgcgcggaggaggcggagctggaag
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Sample Information
×
Sample name
351
Sample type
Tumor
Gender
Female
CpG Island Information
×
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