Basic Information
VIS ID
TVIS10007036
Fusion event
HBV-chr22 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1392
End
1798
Orient
-
Host Sequence
Chromosome
chr22
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
17503843/17022953 (Hg38)
End
17503843/17022953 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7a-3/Downstream/741227;
Nearest TSS
ENST00000624155/Upstream/14731; ENST00000608373/Downstream/44868;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/14649, chr22-CpG: 109/Downstream/13070
Nearby gene
VN1R9P(-683) ;
Upstream sequence
TGCACACTATCTATATTCCTAATGCCCTTTGCCCTCCATCTTTAGAAATCAATTTTTGTTATTTTGTGTTCTCTCATTTTATTTTTAGCACCCAATTCAG
Downstream sequence
TGACAGGCATATAAAATGAATCACATTTGCACAGTCGAATTGAATAAAATGTATGCTAAAGTGGAAAGACTCACTAAAGCAAACAATTAAAAATATATCC
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate