AASDH _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007041
Fusion event
HBV-AASDH integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
428
End
536
Orient
-
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
57252415/56386249 (Hg38)
End
57252415/56386249 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
FRA4B
Target gene
AASDH
miRNAs that regulate target gene
hsa-mir-10b-5p ; hsa-mir-4715-3p ; hsa-mir-3064-3p ; hsa-mir-95-5p ; hsa-mir-605-5p
Nearest miRNA
hsa-mir-12113/Upstream/3673502; hsa-mir-1243/Downstream/4536370;
Nearest TSS
ENST00000502981/Upstream/1950; ENST00000602927/Downstream/1174;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/70268, chr4-CpG: 33/Downstream/1053
Upstream sequence
ctccagcctgggcaacgagagcaaaactccgtctcaaaaaaaaaaaaaaaagaaaaagaaaaagaaaaaaaCAACTATGGATGACCTTTGTGAGACAATG
Downstream sequence
TCTGCAGCAGGCGCTTAAATTATGAGGAATGAGTTCATTTCGCAACATACAGGTAGCGCAGAAGGGTACCTACACATCTATACGATAATTAAGATGTTTC
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate