Basic Information
VIS ID
TVIS10007048
Fusion event
HBV-ADAMTS9-AS2 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1262
End
1568
Orient
-
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
64946657/64960982 (Hg38)
End
64946657/64960982 (Hg38)
Orient
-
Location type
Intron
Target gene
ADAMTS9-AS2
Nearest miRNA
hsa-let-7g/Upstream/4343112; hsa-mir-12124/Downstream/2264482;
Nearest TSS
ENST00000440867/Upstream/272982; ENST00000481004/Downstream/213976;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/272701, chr3-CpG: 63/Downstream/395546
Nearest cancer related gene
ADAMTS9-AS2(TSG, No orient, 0)
Upstream sequence
GAAGTTTGACTTCCTAGAATCATGTCTTTACTTTATTCTGTGAGTTCTCAATATTGCCCACTTGTAATAGGATTTAAAAAACTAGTAACTGGTTATTCCA
Downstream sequence
aggaaaaacaaaaaacaaaaaaCAAAACACCCTAAAATAGCAATTTTATGAATAATAGCAATGAAATGTATTATGATTACCTTTGCTTTCTTTCTCCCCC
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate