Basic Information
VIS ID
TVIS10007050
Fusion event
HBV-chr5 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
980
End
1343
Orient
+
Host Sequence
Chromosome
chr5
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
128745514/129409821 (Hg38)
End
128745514/129409821 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/12674; hsa-mir-103a-1/Downstream/2808028;
Nearest TSS
ENST00000502646/Upstream/315070; ENST00000505791/Downstream/50444;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/314452, chr5-CpG: 165/Downstream/49989
Upstream sequence
ttttcatgtattaactcactggttccccaaattagcatcatgaggtatgtatcatattacctcatgtaactgatgaggagattgaggcccaggatggtta
Downstream sequence
TCGGGGAGAATTTGATGACTTTTTATATCATCCAAATATCCTAGAATTTTCAAAACTGACACTGTAGGGGTGAAGTTTTTCTATATTATTGAAAAGTGGA
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate