Basic Information
VIS ID
TVIS10007058
Fusion event
HBV-chr11 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2932
End
3144
Orient
+
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
80311251/80600207 (Hg38)
End
80311251/80600207 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10392/Upstream/1177981; hsa-let-7a-2/Downstream/1290534;
Nearest TSS
ENST00000527297/Upstream/272296; ENST00000526154/Downstream/162619;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1159047, chr11-CpG: 25/Downstream/2089336
Upstream sequence
cctgaaattaactttcctctcctctactctcaccattctcaattcctttaacagagtgatgacattttcagccttgtgcttaatttagatatacatacac
Downstream sequence
ttgttctcttttctagatggaaagatccttgaaggtcagaaaaatggttattcacattttatccttttctgtatctatggcagatattaTCCTTATCGTG
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate