Basic Information
VIS ID
TVIS10007059
Fusion event
HBV-chr18 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2001
End
2030
Orient
+
Host Sequence
Chromosome
chr18
Cytoband
q23
Reference genome
GRCh37/hg19
Start
76175268/78415268 (Hg38)
End
76175268/78415268 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/5561886;
Nearest TSS
ENST00000575820/Upstream/278045; ENST00000579769/Downstream/65281;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/14824, chr18-CpG: 44/Downstream/14450
Upstream sequence
ctcttgtcccgtatttttcattttctatcttaatttttaacccataagttgggtatcattaggatgtcaccctggccaatgtccacttggacacctctgc
Downstream sequence
acatttaccattttctttacctacaatctcttctctacctcagaccgttctcctggcattattttctttcttcctgggcttcatttactaagagttcttt
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate