ROS1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007063
Fusion event
HBV-ROS1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1313
End
1493
Orient
+
Host Sequence
Chromosome
chr6
Cytoband
q22.1
Reference genome
End
117647569/117326406 (Hg38)
Orient
+
Location type
Exon
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10398/Upstream/10542186; hsa-mir-1202/Downstream/1742641;
Nearest cancer related gene
ROS1(OG, No orient, 0)
Upstream sequence
ataactcaagcacaccctgagaatgaccctgtgtgcgtttcacattctgagctaaggaatctgggagtggcgaacccggagattcactccttatctatga
Downstream sequence
TGCTCTTTCTGCAAAAAATAATAAATACAGAAAATATACATGACAATATACCTGTTATTTCTAGTTGTTCATAGATCTTCTTAGTGACTGAACGCCAGAG
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
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