Basic Information
VIS ID
TVIS10007065
Fusion event
HBV-chr2 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
3023
End
3215
Orient
-
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
32069716/31844647 (Hg38)
End
32069716/31844647 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1301/Upstream/3848198; hsa-mir-10b/Downstream/687506;
Nearest TSS
ENST00000437798/Upstream/40667; ENST00000605811/Downstream/8776;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/262934, chr2-CpG: 174/Downstream/164937
Upstream sequence
cccagctactcgggaagctgaggtgggaggatcacttcagccaggaggttgaggctgcagtgagctaccatcctgctgctgcactccagtctgAAGATCC
Downstream sequence
TTCATCTTTAAAAAAAATAATAATAACGAAAAAAAATAAAAAGAAAGAAGTCCAAATGTGGCAAAAGTCCAGGtctactaatgccagcctgtattattat
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate