Basic Information
VIS ID
TVIS10007068
Fusion event
HBV-LOC110467531 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
520
End
721
Orient
+
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37/hg19
Start
24184912/24002110 (Hg38)
End
24184912/24002110 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC110467531
Nearest miRNA
hsa-mir-10395/Upstream/3602756; hsa-let-7e/Downstream/11120590;
Nearest TSS
ENST00000633603/Upstream/44180; ENST00000597683/Downstream/31295;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/30153, chr19-CpG: 42/Downstream/3791510
Upstream sequence
ccaggcatagtttatcatcttttggtgcctaacacaagcgctcattctccacctgcccagcacagtgggcgagagtggacggtggtgctcccttggcaaa
Downstream sequence
ctggagaggcctcaggatcccgcctcagccagccagcgcatcagccttcaccttcattgcgccacagtggctttcgtgcgagcccctgactcgcacacgt
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate