Basic Information
VIS ID
TVIS10007070
Fusion event
HBV-chr14 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1592
End
1827
Orient
-
Host Sequence
Chromosome
chr14
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
48318483/47849280 (Hg38)
End
48318483/47849280 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/88176; hsa-mir-1185-1/Downstream/2117119;
Nearest TSS
ENST00000550708/Upstream/54188; ENST00000557531/Downstream/642487;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/172894, chr14-CpG: 30/Downstream/1736652
Upstream sequence
aggaagaaaagagagaagaatcaaatagacacaataaaaaatgataaaaggaatattaccactgaccccacagaaatacaaataaccattagaatatact
Downstream sequence
ataaatagctatgcaaaaaactagaaaacatagaagaaatggataaattcctgaacacatacaccctcccaaaactaaaccaggaagaacttgaattcct
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate