Basic Information
VIS ID
TVIS10007071
Fusion event
HBV-LOC105370062 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
405
End
584
Orient
+
Host Sequence
Chromosome
chr12
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
127650953/127166408 (Hg38)
End
127650953/127166408 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
LOC105370062
Nearest miRNA
hsa-let-7i/Upstream/2250749; hsa-mir-3612/Downstream/1127684;
Nearest TSS
ENST00000382841/Upstream/19259; ENST00000535247/Downstream/117875;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/19754, chr12-CpG: 32/Downstream/114323
Upstream sequence
atccgaggccgaccgaggccaaccgaggcgccgcggggctgccgtatcgttccgcctgggcgggattctgacttaagaggcgttcagtcataatcccaca
Downstream sequence
gatggtagcttcgccccattggctcctcagccaaTGGGATCTGATTTTTTAAGCAGTCACAACACTAGACTTTTAATTGAGAAAGCTCTGTAAGCAATTA
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate