Basic Information
VIS ID
TVIS10007076
Fusion event
HBV-chr13 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2134
End
2379
Orient
+
Host Sequence
Chromosome
chr13
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
65439986/64865854 (Hg38)
End
65439986/64865854 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA13B
Nearest miRNA
hsa-mir-1297/Upstream/3665974; hsa-mir-1267/Downstream/1100476;
Nearest TSS
ENST00000623511/Upstream/789843; ENST00000437777/Downstream/1000320;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1021308, chr13-CpG: 92/Downstream/2364522
Upstream sequence
TATAAATTATTGTAACTAAGAATGAGTTGTTCCTATGCAATTTTAACTTAAGAAATAATTACTACTAAAGGTTTGCTTATTCACTGTTTATTTGCTGCTA
Downstream sequence
TTTAGCTAAGGAGAGGGCTGTGGTGGTAGCCCTAGCAATGAAGAGGGAGCCCTGAATCCAAGAAATGTGATATTAGTAGAAATTGTAGGGCTTGAAAAAT
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate