Basic Information
VIS ID
TVIS10007077
Fusion event
HBV-C5orf17 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
656
End
930
Orient
+
Host Sequence
Chromosome
chr5
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
24026194/24026085 (Hg38)
End
24026194/24026085 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
FRA5E
Target gene
C5orf17
Nearest miRNA
hsa-mir-10397/Upstream/6870093; hsa-mir-103a-1/Downstream/7910017;
Nearest TSS
ENST00000502646/Upstream/74521; ENST00000510391/Downstream/327358;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2566342, chr5-CpG: 68/Downstream/1164309
Upstream sequence
acgcatctccgctctcgcaaaggcgccgcgccggcgcaggcgcagagaggcgcgccgcgccggcgcaggcgcagagaggcgcgccgcgccggcgcaggcg
Downstream sequence
caaagatcagagcagaattaaatgaaattgaaaccaaaaaataatacaaaagataaatgaaacaaaagctgattatttgaaaagagagaaaaaattgata
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate