Basic Information
VIS ID
TVIS10007079
Fusion event
HBV-CES5A integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2223
End
2443
Orient
-
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
55937291/55903379 (Hg38)
End
55937291/55903379 (Hg38)
Orient
-
Location type
Intron
Target gene
CES5A
Nearest miRNA
hsa-mir-1225/Upstream/5161002; hsa-mir-11401/Downstream/342141;
Nearest TSS
ENST00000527434/Upstream/28009; ENST00000562822/Downstream/22047;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/70293, chr16-CpG: 152/Downstream/287281
Upstream sequence
gccataactgcctcataaaaggacatgcctagcacagtgcatgaaaccagaaagaggttcaaacaatatttgttTTTAACAAACTAGTTAATGAAGAAAA
Downstream sequence
AAAGAAACAAAGGAATTGAGTACAGAATATTGTCACTGTGCAGTgatttggggcaagatatatgagttctggtcttgtttctgccattatgagtattttt
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate