Basic Information
VIS ID
TVIS10007085
Fusion event
HBV-chr8 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
265
End
541
Orient
-
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
GRCh37/hg19
Start
120290505/119278265 (Hg38)
End
120290505/119278265 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA8C ; FRA8E
Nearest miRNA
hsa-mir-12123/Upstream/2403465; hsa-mir-10400/Downstream/46906;
Nearest TSS
ENST00000518652/Upstream/31417; ENST00000520082/Downstream/138041;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/69283, chr8-CpG: 57/Downstream/137893
Upstream sequence
ATTGATTCATTTAGgagactgagtctcactctgtcacccagcctggagtgcagtggcatgatctcagctcactgcaacctccacctcccaggttcaagct
Downstream sequence
aatgaccataggcttttagaaacagctaagccatgtatagaatgctttgctgtttagaaactttttctgctagataccctaatctccctgaagtttaaac
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
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