DPYSL3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007086
Fusion event
HBV-DPYSL3 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2149
End
2415
Orient
+
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
GRCh37/hg19
Start
146877873/147498310 (Hg38)
End
146877873/147498310 (Hg38)
Orient
+
Location type
Intron
Target gene
DPYSL3
miRNAs that regulate target gene
hsa-mir-197-3p ; hsa-mir-375 ; hsa-mir-26b-5p ; hsa-mir-423-3p ; hsa-mir-218-5p ; hsa-mir-3685 ; hsa-mir-155-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-3667-3p ; hsa-mir-4738-5p ; hsa-mir-5586-5p
Nearest miRNA
hsa-mir-10397/Upstream/3818339; hsa-mir-103a-1/Downstream/1564003;
Nearest TSS
ENST00000502646/Upstream/44044; ENST00000627433/Downstream/11225;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/43935, chr5-CpG: 93/Downstream/10877
Upstream sequence
GCTGTGAAGCCAGTAGCTATTTTAAAAGTGCTGGCTGCAGGATTAAGCCAACCCTTTACAACTGGCCCAGACCGTAATGGCCATTTCTTCTTAAAAAAAA
Downstream sequence
accacgttttctttatccagtctatcagtgaagggcatttaggttgattccatgtcattgctattgggaatagtgctgcaatgaacatacacgtgcatgt
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate